⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103908 | 0.82 | — | — | |
| SCHEMBL12431782 | 0.78 | — | — | |
| SCHEMBL981072 | 0.72 | DGAT1 (0.38) | — | |
| SCHEMBL31047131 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL8729386 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL4532178 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL27693428 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL1274256 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL2106039 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL14936244 | 0.70 | DGAT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894402-B1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3765546-A1 | COMPOSITIONS, METHOD OF BONDING, AND BONDED ASSEMBLY | 3M Innovative Properties Company (US) | 2021-01-20 | — | — | EP | disclosed |
| CN-107001286-B | Dihydropyrimidine-2-one compounds and medicinal use thereof | 日本烟草产业株式会社 | 2020-07-07 | — | — | CN | disclosed |
| WO-2019175709-A1 | COMPOSITIONS, METHOD OF BONDING, AND BONDED ASSEMBLY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-09-19 | — | — | WO | disclosed |
| US-9062032-B2 | Aminoalkyl-substituted N-thienylbenzamide derivative | ASTELLAS PHARMA INC. (JP) | 2015-06-23 | — | — | US | disclosed |
| US-20150031727-A1 | AMINOALKYL-SUBSTITUTED N-THIENYLBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2015-01-29 | — | — | US | disclosed |
| WO-2015007451-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-22 | — | — | WO | disclosed |
| CN-102119047-B | Heteroaryl derivatives as DGAT1 inhibitors | NOVARTIS AG | 2014-09-24 | — | — | CN | disclosed |
| CN-102753533-B | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LTD | 2014-07-30 | — | — | CN | disclosed |
| EP-1838315-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | SANOFI SA (FR) | 2014-03-12 | — | — | EP | disclosed |
| CN-102753533-A | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-102119047-A | Heteroaryl derivatives as DGAT1 inhibitors | NOVARTIS AG | 2011-07-06 | — | — | CN | disclosed |
| CN-1950389-B | Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs | KISSEI PHARMACEUTICAL | 2011-01-19 | — | — | CN | disclosed |
| CN-101595103-A | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2009-12-02 | — | — | CN | disclosed |
| EP-1838315-A1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | sanofi-aventis (FR) | 2007-10-03 | — | — | EP | disclosed |
| CN-1950389-A | Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs | KISSEI PHARMACEUTICAL (JP) | 2007-04-18 | — | — | CN | disclosed |
| WO-2006074813-A1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | SANOFI-AVENTIS (DE) | 2006-07-20 | — | — | WO | disclosed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | disclosed |