SCHEMBL981072

SCHEMBL981072

COC(=O)C(C)(C)N=C=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.38
KCNN4 O15554 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664669 0.79 DGAT1 (0.37) DGAT1
SCHEMBL14936244 0.79 DGAT1 (0.41) DGAT1
SCHEMBL2647194 0.77 DGAT1 (0.35) DGAT1
SCHEMBL30234219 0.76 GAA (0.36)
SCHEMBL7839348 0.76 MEN1 (0.40)
SCHEMBL27231084 0.74 DGAT1 (0.33) DGAT1
SCHEMBL14299531 0.74 DGAT1 (0.44) DGAT1KCNN4
SCHEMBL28678 0.74 DGAT1 (0.44) DGAT1KCNN4
SCHEMBL28677 0.74 DGAT1 (0.44) DGAT1KCNN4
SCHEMBL10449706 0.73 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
CN-117836344-A Dual cure resin composition comprising uretdione containing compounds and use thereof in 3D printing 巴斯夫欧洲公司 2024-04-05 CN disclosed
WO-2024033289-A1 A PHOTOCURABLE OLIGOMER CONTAINING URETDIONE GROUPS, METHOD OF PREPARING THE OLIGOMER AND DUAL-CURE RESIN COMPOSITION CONTAINING THE OLIGOMER THEREOF BASF SE (DE) 2024-02-15 WO disclosed
US-11834421-B2 Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2023-12-05 US disclosed
CN-111741948-B Saturated ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof 日本烟草产业株式会社 2023-11-10 CN disclosed
EP-3760619-B1 SATURATED RING-CONDENSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUND, AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC (JP) 2023-10-25 EP disclosed
WO-2023012000-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2023-02-09 WO disclosed
CN-111868130-B Composition, bonding method and assembly 3M创新有限公司 2022-06-24 CN disclosed
CN-111788246-B Composition, bonding method and bonded assembly 3M创新有限公司 2022-06-10 CN disclosed
US-20220119355-A1 SATURATED-RING-FUSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUNDS AND PHARMACEUTICAL USE THEREOF SHIONOGI & CO., LTD. (JP) 2022-04-21 US disclosed
US-4407814-A ANTIANDROGENS, 3-(HALO- AND/OR TRIFULOROMETHYL-PHENYL)-4,4-DIMETHYL-HYDANTOINS AND IMINO DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1983-10-04 US disclosed
EP-0001813-B1 IMIDAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR USE IN THIS PROCESS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE USE OF THE ACTIVE COMPOUNDS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-11-04 EP disclosed
US-4234736-A FLUOROPHENYL DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1980-11-18 US disclosed
EP-0000023-B1 OMEGA-SUBSTITUTED PENTYL UREAS, THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1980-07-23 EP disclosed
US-4188401-A Combating fungi with 1-(ω-substituted pentyl)-3-(2-cyano-acetyl)-ureas BAYER AKTIENGESELLSCHAFT (DE) 1980-02-12 US disclosed
EP-0001813-A1 Imidazolidine derivatives, process for their preparation, intermediates for use in this process, pharmaceutical compositions containing them and the use of the active compounds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-05-16 EP disclosed
EP-0000023-A1 Omega-substituted pentyl ureas, their preparation and their use as fungicides BAYER AG (DE) 1978-12-20 EP disclosed
US-4079147-A Fungicidally active derivatives of carbamic acid oxime-esters of isonitrosocyanoacetic acid BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-4000274-A PHARMACEUTICAL COMPOSITIONS CONTAINING AN N-ARYL-N'-(PHENYL-OR-PHENOXY-ALKYL)-PIPERAZINE AND METHOD OF USE BOEHRINGER INGELHEIM GMBH (DT) 1976-12-28 US disclosed
US-3941789-A CNS DEPRESSANT, ADRENOLYTIC, ANTIPHLOGISTIC, ANALGESIC, ANTIHISTAMINE, ANTICHOLESTEROL BOEHRINGER INGELHEIM GMBH (DT) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834421-B2 Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof RORC, RORB, RORA DGAT1 1871/4885KCNN4 1777/4885NPSR1 253/4885
US-20220119355-A1 SATURATED-RING-FUSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUNDS AND PHARMACEUTICAL USE THEREOF RORC, RORB, RORA DGAT1 1871/4885KCNN4 1777/4885NPSR1 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.