Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.59 |
| ▸ | FLT4 | P35916 | 5/20 | 0.59 |
| ▸ | KDR | P35968 | 5/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 9/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.46 |
| ▸ | VCP | P55072 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318254 | 0.81 | VCP (0.58) | FLT1FLT4KDRIMPDH2RIPK2 | |
| SCHEMBL5319793 | 0.81 | IMPDH2 (0.60) | FLT1FLT4KDRIMPDH2RIPK2 | |
| SCHEMBL5338884 | 0.79 | FLT1 (0.59) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5316678 | 0.77 | FLT1 (0.60) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5464876 | 0.77 | FLT1 (0.77) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5480372 | 0.77 | FLT1 (0.69) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5319878 | 0.76 | FLT1 (0.76) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5469587 | 0.76 | KDR (0.76) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5480404 | 0.76 | KDR (0.97) | FLT1FLT4KDRIMPDH2VCP | |
| SCHEMBL5476166 | 0.75 | FLT1 (0.66) | FLT1FLT4KDRIMPDH2VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |