Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319948 | 1.00 | LMNA (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL19613777 | 0.90 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL20741833 | 0.86 | PTPN1 (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL7889307 | 0.84 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL5322879 | 0.83 | POLB (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5320321 | 0.83 | POLB (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL14436494 | 0.83 | POLB (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5320327 | 0.83 | POLB (0.43) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL14819156 | 0.82 | LGALS3 (0.50) | POLB | |
| SCHEMBL14819208 | 0.82 | LGALS3 (0.50) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093769-A1 | OLIGOSACCHARIDE BIOSYNTHESIS INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |