Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14819156 | 0.92 | LGALS3 (0.50) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL14819208 | 0.92 | LGALS3 (0.50) | LGALS3LGALS9LGALS1LGALS7; LGALS7BPOLB | |
| SCHEMBL2483143 | 0.85 | LGALS3 (0.48) | LGALS3LGALS9LGALS1LGALS7; LGALS7BSELP | |
| SCHEMBL17241861 | 0.85 | LGALS3 (0.48) | LGALS3LGALS9LGALS1LGALS7; LGALS7BSELP | |
| SCHEMBL20226186 | 0.85 | LGALS3 (0.48) | LGALS3LGALS9LGALS1LGALS7; LGALS7BSELP | |
| SCHEMBL17241860 | 0.85 | LGALS3 (0.48) | LGALS3LGALS9LGALS1LGALS7; LGALS7BSELP | |
| SCHEMBL19613777 | 0.85 | LMNA (0.44) | LMNAKMT2ALGALS3LGALS9LGALS1 | |
| SCHEMBL5319950 | 0.84 | LMNA (0.43) | LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL5319948 | 0.84 | LMNA (0.43) | LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL13367679 | 0.83 | MAPK1 (0.49) | LMNAKMT2ALGALS3LGALS9LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6168934-B1 | EFFICIENT GLYCOSYLATION BY MIXING ACCEPTOR SACCHARIDE, DONOR MONOSACCHARIDE, ACTIVATING NUCLEOTIDE, ACTIVATED DONOR MONOSACCHARIDE REGENERATING SYSTEM, PYROPHOSPHATE SCAVENGER, AND GLYCOSYLTRANSFERASE IN AN AQUEOUS MEDIUM | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-02 | — | — | US | disclosed |
| EP-0576592-B1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5759823-A | MIXING IN AQUEOUS MEDIUM ACTIVATED DONOR MONOSACCHARIDE WITH ACCEPTOR SACCHARIDE IN PRESENCE OF GLYCOSYLTRANSFERASE, MAINTAINING TO GLYCOSYLATE ACCEPTOR SACCHARIDE | SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-02 | — | — | US | disclosed |
| US-5593887-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0576592-A4 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5461143-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0576592-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016640-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-10-01 | — | — | WO | disclosed |