Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772272 | 0.81 | ALDH1A1 (0.81) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4881337 | 0.77 | ALDH1A1 (0.69) | ALDH1A1MAPTTAAR1SMN1; SMN2KDM4E | |
| SCHEMBL15998952 | 0.75 | ALDH1A1 (0.74) | ALDH1A1MAPTTAAR1SMN1; SMN2KDM4E | |
| SCHEMBL4878034 | 0.75 | ALDH1A1 (0.61) | ALDH1A1S1PR4MAPTTAAR1SMN1; SMN2 | |
| SCHEMBL4885182 | 0.74 | ALDH1A1 (0.44) | ALDH1A1S1PR4MAPTTAAR1SMN1; SMN2 | |
| SCHEMBL9772342 | 0.74 | MAPT (0.62) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4874761 | 0.73 | ALDH1A1 (0.80) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL10642418 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL14232240 | 0.72 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4879015 | 0.72 | MAPT (0.49) | ALDH1A1MAPTTAAR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536655-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 深圳开悦生命科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-115536655-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 深圳开悦生命科技有限公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-1841428-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | Immusol Incorporated (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006078754-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | IMMUSOL INCORPORATED (US) | 2006-07-27 | — | — | WO | disclosed |