Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002902 | 0.86 | ALDH1A1 (0.52) | RECQLGAAALDH1A1NPSR1NPC1 | |
| SCHEMBL11531301 | 0.79 | GAA (0.59) | RECQLGAAALDH1A1NPSR1MGLL | |
| SCHEMBL11527812 | 0.76 | GAA (0.65) | RECQLGAAALDH1A1NPSR1MGLL | |
| SCHEMBL21163154 | 0.76 | GAA (0.59) | RECQLGAAALDH1A1NPSR1MGLL | |
| SCHEMBL5463525 | 0.74 | LMNA (0.81) | GAAALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL3190624 | 0.74 | ALDH1A1 (0.69) | GAAALDH1A1NPSR1SMN1; SMN2HTT | |
| SCHEMBL10866296 | 0.74 | RECQL (0.69) | RECQLGAAALDH1A1NPSR1LMNA | |
| SCHEMBL10773968 | 0.74 | AKT1 (0.64) | RECQLNPC1RAB9APTGES | |
| SCHEMBL3078247 | 0.73 | RECQL (0.59) | RECQLGAAALDH1A1NPSR1MGLL | |
| SCHEMBL9714192 | 0.73 | MGLL (0.52) | RECQLGAAALDH1A1NPSR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007090134-A2 | USE OF VANILLOID RECEPTOR-1 ANTAGONISTS FOR THE PREVENTION AND TREATMENT OF GLAUCOMA | ALCON MANUFACTURING, LTD. (US) | 2007-08-09 | — | — | WO | claimed |