Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | MGLL | Q99685 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531301 | 0.80 | GAA (0.59) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL3190624 | 0.78 | ALDH1A1 (0.69) | GAAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL5463525 | 0.78 | LMNA (0.81) | GAALMNAALDH1A1NPSR1HTT | |
| SCHEMBL11527812 | 0.77 | GAA (0.65) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL3078247 | 0.77 | RECQL (0.59) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL3072973 | 0.76 | MGLL (0.65) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL11835849 | 0.76 | MGLL (0.65) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL3065466 | 0.76 | RECQL (0.67) | GAAMGLLLMNARECQLALDH1A1 | |
| SCHEMBL5081872 | 0.76 | ALDH1A1 (0.63) | GAALMNAALDH1A1NPSR1HTT | |
| SCHEMBL5320120 | 0.76 | RECQL (0.62) | GAAMGLLLMNARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968297-B2 | Thiourea group IV transition metal catalysts and polymerization systems | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190202950-A1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968297-B2 | Thiourea group IV transition metal catalysts and polymerization systems | TTI1, TST, TTI2 | GAA 2242/4885MGLL 3124/4885LMNA 4484/4885 |
| US-20190202950-A1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | TTI1, TST, TTI2 | GAA 2242/4885MGLL 3124/4885LMNA 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.