Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413642 | 0.85 | CTSL (0.40) | ALDH1A1POLBCTSLCTSSCTSK | |
| SCHEMBL3303697 | 0.80 | CTSL (0.43) | CTSLCTSSCTSKSMN1; SMN2NPC1 | |
| SCHEMBL10242213 | 0.77 | ATM (0.46) | KMT2AMEN1CTSLCTSSCTSK | |
| SCHEMBL27684880 | 0.76 | CYP19A1 (0.41) | L3MBTL1 | |
| SCHEMBL7408571 | 0.69 | MAPT (0.45) | KMT2AALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL10434937 | 0.69 | TSHR (0.44) | KMT2AMEN1ALDH1A1POLBCTSL | |
| SCHEMBL9271702 | 0.69 | MAPT (0.37) | KMT2AALDH1A1CTSLCTSSCTSK | |
| SCHEMBL17965952 | 0.68 | PGR (0.57) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL532486 | 0.68 | KMT2A (0.49) | KMT2AMEN1ALDH1A1POLBRAB9A | |
| SCHEMBL531388 | 0.68 | KMT2A (0.49) | KMT2AMEN1ALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |