Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805707 | 0.83 | AHR (0.45) | AHRS100A4PPOXALDH1A1MAPK1 | |
| SCHEMBL21031787 | 0.83 | AHR (0.45) | AHRS100A4PPOXALDH1A1MAPK1 | |
| SCHEMBL2753221 | 0.79 | ALOX15 (0.38) | AHRS100A4ALDH1A1MAPK1CA1 | |
| SCHEMBL26805882 | 0.79 | GCGR (0.41) | AHRS100A4ALDH1A1MAPK1SRD5A2 | |
| SCHEMBL571071 | 0.79 | ALDH1A1 (0.54) | S100A4ALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL434492 | 0.79 | AHR (0.57) | AHRALDH1A1SRD5A2TSHRTP53 | |
| SCHEMBL20599056 | 0.78 | S100A4 (0.46) | AHRS100A4NPBWR1PPOXALDH1A1 | |
| SCHEMBL24810017 | 0.76 | GCGR (0.46) | MAPK1TSHRTP53 | |
| SCHEMBL15622693 | 0.76 | TSHR (0.46) | AHRS100A4ALDH1A1MAPK1TSHR | |
| SCHEMBL20023629 | 0.76 | CYP1A2 (0.54) | S100A4ALDH1A1MAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |