Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936412 | 0.72 | — | — | |
| SCHEMBL88154 | 0.67 | — | — | |
| SCHEMBL7028189 | 0.67 | — | — | |
| SCHEMBL6469555 | 0.67 | — | — | |
| Diallyl Sulfide SCHEMBL9376569 | 0.65 | ALOX5 (0.58) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL11031750 | 0.65 | — | — | |
| SCHEMBL4239375 | 0.64 | TRPA1 (0.47) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL75409 | 0.64 | LMNA (0.47) | ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL1270185 | 0.64 | LMNA (0.47) | ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL30535 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011710-A1 | METHODS OF TREATING VIRAL INFECTIONS | CHIMERIX, INC. (US) | 2011-01-27 | — | — | WO | claimed |
| EP-2841162-A1 | A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE | Chimerix, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2770834-A1 | HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION | Chimerix, Inc. (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013163509-A1 | A METHOD OF MITIGATING VIRUS ASSOCIATED END-ORGAN DAMAGE | CHIMERIX, INC. (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013063436-A1 | HEXADECYLOXYPROPYL CIDOFOVIR FOR THE TREATMENT OF DOUBLE-STRANDED DNA VIRUS INFECTION | CHIMERIX, INC. (US) | 2013-05-02 | — | — | WO | disclosed |
| EP-1868628-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | Chimerix, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110655-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | CHIMERIX, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-5851548-A | Liposomes containing cationic lipids and vitamin D | GEN-PROBE INCORPORATED (US) | 1998-12-22 | — | — | US | disclosed |
| US-5759519-A | Method for the intracellular delivery of biomolecules using thiocationic lipids | GEN-PROBE INCORPORATED (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756352-A | CATIONIC CHARGES FOR LIPIDS USED IN DIAGNOSIS | GEN-PROBE INCORPORATED (US) | 1998-05-26 | — | — | US | disclosed |
| US-5739271-A | DRUG DELIVERY OF OLIGONUCLEOTIDES, NUCLEIC ACIDS, PEPTIDES, IMAGES, AND PROTEINS | GEN-PROBE INCORPORATED (US) | 1998-04-14 | — | — | US | disclosed |
| US-5711964-A | CELLULAR METABOLISM AND CATIONIC LIPIDS | UNITED STATES OF AMERICA (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1996040627-A2 | THIOCATIONIC LIPIDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | GEN-PROBE INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0747351-A2 | Thiocationic lipids, pharmaceutical compositions and methods of use thereof | GEN-PROBE INCORPORATED (US) | 1996-12-11 | — | — | EP | disclosed |
| US-4087466-A | NONIONIC SURFACTANTS | L'OREAL (FR) | 1978-05-02 | — | — | US | disclosed |
| US-4058629-A | Polyhydroxyl monosulfoxide shampoo compositions | L'OREAL (FR) | 1977-11-15 | — | — | US | disclosed |
| US-3984480-A | Polyhydroxyl monosulfoxide surfactant | L'OREAL (FR) | 1976-10-05 | — | — | US | disclosed |
| US-3966398-A | Hair dyeing composition containing a non-ionic surfactant | L'OREAL (FR) | 1976-06-29 | — | — | US | disclosed |