Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320949 | 0.87 | HTT (0.42) | PTPN2PTPN1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4035788 | 0.79 | HTR2A (0.47) | MAPTALDH1A1TDP1 | |
| SCHEMBL7386151 | 0.79 | KMT2A (0.46) | MAPTALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL9774304 | 0.79 | GAA (0.47) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6510960 | 0.78 | ALDH1A1 (0.45) | PTPN2PTPN1POLBALDH1A1TDP1 | |
| SCHEMBL8997420 | 0.77 | HTT (0.35) | POLBMAPTPKMMAPK1CRBN | |
| SCHEMBL617412 | 0.76 | RAB9A (0.42) | SMN1; SMN2POLBALDH1A1KMT2APKM | |
| SCHEMBL660307 | 0.74 | GAA (0.43) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL16398974 | 0.74 | PTPN2 (0.51) | PTPN2PTPN1SMN1; SMN2POLBCHRM2 | |
| SCHEMBL7633022 | 0.73 | MEN1 (0.60) | PTPN2PTPN1SMN1; SMN2POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417927-A1 | Detection and treatment of infections with immunoconjugates | IMMUNOMEDICS, INC. (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1991002541-A1 | DETECTION AND TREATMENT OF INFECTIONS WITH IMMUNOCONJUGATES | IMMUNOMEDICS, INC. (US) | 1991-03-07 | — | — | WO | disclosed |