Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762334 | 0.91 | CA12 (0.39) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL532116 | 0.90 | ACHE (0.38) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL532307 | 0.85 | BCHE (0.36) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL532709 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL13060232 | 0.78 | CA12 (0.37) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL13003126 | 0.78 | CA12 (0.36) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL532306 | 0.76 | BCHE (0.38) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL13815245 | 0.76 | MEN1 (0.42) | ALDH1A1HPGD | |
| SCHEMBL13955280 | 0.72 | GSTP1 (0.40) | ALDH1A1 | |
| SCHEMBL13060231 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7851606-B2 | Negatively charged minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-7851606-B2 | Negatively charged minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-7582739-B2 | Negatively charged minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-6727356-B1 | AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION | EPOCH PHARMACEUTICALS, INC. | 2004-04-27 | — | — | US | disclosed |
| US-6699975-B2 | OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION | EPOCH BIOSCIENCES, INC. | 2004-03-02 | — | — | US | disclosed |
| US-6653473-B2 | Nucleotide sequences for use as diagnostic tool in genetic analysis | EPOCH BIOSCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | EPOCH BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
| EP-1235938-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | ELITECHGROUP, INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2001042505-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | KDM4E 4634/4885ALDH1A1 2350/4885HPGD 2806/4885 |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | KDM4E 4634/4885ALDH1A1 2350/4885HPGD 2806/4885 |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | KDM4E 4651/4885ALDH1A1 2211/4885HPGD 2815/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | KDM4E 3864/4885ALDH1A1 3183/4885HPGD 2930/4885 |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | PCNA, NCL, HNRNPH3 | KDM4E 3510/4885ALDH1A1 2862/4885HPGD 4393/4885 |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | DCLRE1B, SNRPE, ZFR | KDM4E 4757/4885ALDH1A1 2641/4885HPGD 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.