Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537880 | 0.83 | MAPT (0.51) | MEN1KMT2ACYP1A2CYP2C9ALK | |
| SCHEMBL25897326 | 0.71 | HIF1A (0.36) | MEN1KMT2ACYP1A2CYP2C9ALK | |
| SCHEMBL29202241 | 0.71 | DRD4 (0.42) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL26654657 | 0.70 | TP53 (0.43) | MEN1KMT2ACYP1A2CYP2C9LMNA | |
| SCHEMBL10703573 | 0.68 | RAB9A (0.57) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL29202242 | 0.67 | LMNA (0.38) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL24156660 | 0.67 | TP53 (0.38) | MEN1KMT2ACYP1A2CYP2C9MAPT | |
| SCHEMBL24156933 | 0.67 | DRD2 (0.34) | MEN1KMT2ACYP1A2CYP2C9ALK | |
| SCHEMBL4624964 | 0.66 | — | — | |
| SCHEMBL29202211 | 0.66 | LMNA (0.43) | MEN1KMT2ACYP1A2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964639-A | Pyridazine compound containing benzo heterocyclic structure, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-03 | — | — | CN | disclosed |