Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7626366 | 0.99 | LMNA (0.50) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL5317203 | 0.81 | ADRA2A (0.56) | ADRB2ADRB1ADRB3ADRA2BADRA2C | |
| SCHEMBL16776722 | 0.80 | LMNA (0.56) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL21635531 | 0.80 | LMNA (0.56) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL8213401 | 0.79 | ADRB1 (0.56) | HPGDSMN1; SMN2ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6420499 | 0.79 | LMNA (0.55) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL9506665 | 0.76 | LMNA (0.59) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL3336139 | 0.73 | KDM4E (0.73) | KDM4ELMNAHPGDALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8213972 | 0.72 | LMNA (0.50) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL11251333 | 0.72 | NPC1 (0.48) | KDM4ELMNAHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087367-A9 | METHODS AND COMPOSITIONS FOR MODULATING THE MOBILIZATION OF STEM CELLS | SINAI SCHOOL MEDICINE (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007087367-A2 | METHODS AND COMPOSITIONS FOR MODULATING THE MOBILIZATION OF STEM CELLS | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2007-08-02 | — | — | WO | disclosed |
| EP-1490090-A4 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | NEW RIVER PHARMACEUTICALS INC (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005099699-A1 | COMBINATION OF (S)-AMLODIPINE AND A BETA-BLOCKER, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| EP-1357928-A4 | A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME | NEW RIVER PHARMACEUTICALS INC (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1490090-A2 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | New River Pharmaceuticals Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1357928-A2 | A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME | New River Pharmaceuticals Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2003079972-A2 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | NEW RIVER PARMACEUTICALS INC. (US) | 2003-10-02 | — | — | WO | disclosed |
| WO-2003020200-A2 | A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME | NEW RIVER PHARMACEUTICALS INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| EP-1146865-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF DEXTRO- AND LAEVO- ISOMERS OF SOTALOL | Torrent Pharmaceuticals Ltd (IN) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000045807-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF DEXTRO- AND LAEVO- ISOMERS OF SOTALOL | SANKARANARAYANAN ALANGUDI (IN) | 2000-08-10 | — | — | WO | disclosed |