Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321902 | 0.79 | KDM4E (0.51) | ADRB1ADRB3ADRB2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7626366 | 0.78 | LMNA (0.50) | ADRB1ADRB3ADRB2NPC1RAB9A | |
| SCHEMBL8213400 | 0.76 | ADRB3 (0.67) | ADRB1ADRB3ADRB2DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL11697572 | 0.75 | ADRB3 (0.66) | ADRB1ADRB3ADRB2DRD3DRD2 | |
| SCHEMBL11696549 | 0.75 | ADRB3 (0.66) | ADRB1ADRB3ADRB2DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL501158 | 0.74 | ALOX15 (0.61) | ADRB1ADRB3SIGMAR1 | |
| SCHEMBL11696035 | 0.72 | GRIN1 (0.55) | ADRB1ADRB3ADRB2NPC1RAB9A | |
| SCHEMBL7117594 | 0.72 | DRD2 (0.50) | ADRB3DRD3DRD2DRD4 | |
| SCHEMBL7117599 | 0.72 | DRD2 (0.50) | ADRB3DRD3DRD2DRD4 | |
| SCHEMBL16776722 | 0.72 | LMNA (0.56) | ADRB1ADRB3ADRB2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | disclosed |