SCHEMBL5322012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5320168	0.89	ALOX15 (0.56)	KMT2AALOX15BLMPMP22SLC7A5
	SCHEMBL1236551	0.89	ALOX15 (0.56)	KMT2AALOX15BLMPMP22SLC7A5
	SCHEMBL8398141	0.88	GABRP (0.50)	SLC7A5GABRPGABRDGABRA1GABRB1
	SCHEMBL2420751	0.81	GSR (0.48)	KMT2ABLMSLC7A5GABRPGABRD
	SCHEMBL8666519	0.81	SLC1A2 (0.50)	SLC7A5ALDH1A1DPP4DPP8DPP9
	SCHEMBL31370048	0.81	SLC1A2 (0.50)	SLC7A5ALDH1A1DPP4DPP8DPP9
	SCHEMBL5296286	0.81	SLC1A2 (0.50)	SLC7A5ALDH1A1DPP4DPP8DPP9
	SCHEMBL8015462	0.81	GSR (0.48)	KMT2ABLMSLC7A5GABRPGABRD
	SCHEMBL2420748	0.81	GSR (0.48)	KMT2ABLMSLC7A5GABRPGABRD
	SCHEMBL5319928	0.79	GSR (0.57)	KMT2AALOX15BLMSLC7A5LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.