Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 3/20 | 0.55 |
| ▸ | PLAUR | Q03405 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487367 | 0.82 | RAB9A (0.59) | PLAUPLAURALDH1A1MEN1KMT2A | |
| SCHEMBL6192045 | 0.81 | RAB9A (0.62) | PLAUPLAURALDH1A1MEN1KMT2A | |
| SCHEMBL5321539 | 0.80 | ALDH1A1 (0.58) | PLAUPLAURALDH1A1MEN1KMT2A | |
| SCHEMBL11251072 | 0.78 | SLC6A4 (0.55) | PLAUPLAURALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9011146 | 0.76 | NPC1 (0.65) | ALDH1A1MEN1KMT2ACAPN1LMNA | |
| SCHEMBL5429317 | 0.75 | MEN1 (0.55) | PLAUPLAURALDH1A1MEN1KMT2A | |
| SCHEMBL252026 | 0.74 | HPGD (0.79) | MAOBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7129676 | 0.74 | HPGD (0.79) | MAOBALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1597472 | 0.73 | HPGD (0.76) | MAOBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12777929 | 0.72 | MAOB (0.68) | MAOBALDH1A1KMT2APOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096251-A1 | INHIBITORS OF CPT IN THE CENTRAL NERVOUS SYSTEM AS ANTIDIABETIC AND/OR ANTI-OBESITY DRUGS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096251-A1 | INHIBITORS OF CPT IN THE CENTRAL NERVOUS SYSTEM AS ANTIDIABETIC AND/OR ANTI-OBESITY DRUGS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-08-30 | — | — | WO | disclosed |