Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | PLAUR | Q03405 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192045 | 0.98 | RAB9A (0.62) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL11251072 | 0.86 | SLC6A4 (0.55) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL20791842 | 0.85 | SLC6A2 (0.49) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL18375212 | 0.85 | SLC6A2 (0.49) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL4143905 | 0.85 | LMNA (0.71) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL27910314 | 0.85 | RAB9A (0.69) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL5321539 | 0.84 | ALDH1A1 (0.58) | ALDH1A1POLBL3MBTL1LMNATSHR | |
| Hydrochloric Acid SCHEMBL9096753 | 0.83 | LMNA (0.69) | RAB9AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL5322283 | 0.82 | MAOB (0.55) | ALDH1A1POLBL3MBTL1LMNATSHR | |
| SCHEMBL5429317 | 0.79 | MEN1 (0.55) | RAB9AALDH1A1POLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | claimed |
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |