Xylose

Xylose

SCHEMBL5322348

CCCC.O=C[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
AKR1B1 P15121 1/20 0.39
KDM4E B2RXH2 2/20 0.37
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
MPI P34949 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
TOP1 P11387 1/20 0.31
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL5073109 0.93 LMNA (0.48) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL20298307 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL17376028 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL27662059 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL624787 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL23066320 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL9723246 0.93 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL28247070 0.93 LMNA (0.50) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL9824366 0.91 LMNA (0.43) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL6243082 0.91 LMNA (0.48) LMNAL3MBTL1TDP1AKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180180626-A1 A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT STC BIOLOGICS INC (US) 2018-06-28 US disclosed
US-9868973-B2 Method for optimizing post-translational modifications on recombinant proteins STC BIOLOGICS, INC. (US) 2018-01-16 US disclosed
US-20160340706-A1 Method for Optimizing Post-Translational Modifications on Recombinant Proteins STC BIOLOGICS, INC. 2016-11-24 US disclosed
EP-3094639-A1 METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS Leszcyniecka, Magdalena (US) 2016-11-23 EP disclosed
WO-2015106276-A1 METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS LESZCYNIECKA MAGDALENA (US) 2015-07-16 WO disclosed
WO-2007099392-A2 CONVERGENT SYNTHESIS OF CARBOHYDRATE BUILDING BLOCKS SWISS FEDERAL INSTITUTE OF TECHNOLOGY (US) 2007-09-07 WO disclosed