Demannose

Demannose

SCHEMBL5073109

CCCC.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 2/20 0.40
PDE4A P27815 1/20 0.40
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
AKR1B1 P15121 1/20 0.37
TOP1 P11387 1/20 0.33
MPI P34949 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL27911471 0.94 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL7958057 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylose SCHEMBL5322348 0.93 LMNA (0.43) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL537703 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL329074 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL28146511 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL3872401 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Galactose SCHEMBL6900501 0.93 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL2341216 0.91 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL9938071 0.91 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622357-B A kind of synthetic method of Dapagliflozin impurity 合肥华方医药科技有限公司 2017-11-17 CN disclosed
CN-102046751-B High porosity abrasive articles and methods of manufacturing same SAINT GOBAIN ABRASIVES INC 2013-08-28 CN disclosed
CN-102046751-A High porosity abrasive articles and methods of manufacturing same SAINT GOBAIN ABRASIVES INC 2011-05-04 CN disclosed
EP-1986567-A2 DRUG DELIVERY STENT WITH EXTENDED IN VIVO DRUG RELEASE Conor Medsystems, Inc. (US) 2008-11-05 EP disclosed
WO-2008024626-A2 BIORESORBABLE STENT WITH EXTENDED IN VIVO RELEASE OF ANTI-RESTENOTIC AGENT INNOVATIONAL HOLDINGS LLC (US) 2008-02-28 WO disclosed
EP-1858442-A2 EXPANDABLE MEDICAL DEVICE WITH OPENINGS FOR DELIVERY OF MULTIPLE BENEFICIAL AGENTS Conor Medsystems, Inc. (US) 2007-11-28 EP disclosed
WO-2007092833-A2 DRUG DELIVERY STENT WITH EXTENDED IN VIVO DRUG RELEASE CONOR MEDSYSTEMS, INC. (US) 2007-08-16 WO disclosed
WO-2006098889-A2 EXPANDABLE MEDICAL DEVICE WITH OPENINGS FOR DELIVERY OF MULTIPLE BENEFICIAL AGENTS CONOR MEDSYSTEMS, INC. (US) 2006-09-21 WO disclosed
WO-2006099381-A1 DRUG DELIVERY STENT WITH EXTENDED IN VIVO AND IN VITRO RELEASE OF ANTI-INFLAMMATORY CONOR MEDSYSTEMS, INC. (US) 2006-09-21 WO disclosed
US-6620921-B1 1,2,3,5,6-penta-O-propanoyl-beta-D-glucofuranose in crystalline form; prepared by reacting D-glucose, boric acid and propanoic anhydride; useful for preparation of glycosides INDUSTRIAL RESEARCH LIMITED (NZ) 2003-09-16 US disclosed
WO-2001036435-A1 GLUCOFURANOSES INDUSTRIAL RESEARCH LIMITED (NZ) 2001-05-25 WO disclosed