Xylose

Xylose

SCHEMBL624787

CCO.O=C[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Xylose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 2/20 0.38
PDE4A P27815 1/20 0.38
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
MPI P34949 1/20 0.33
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
TOP1 P11387 1/20 0.32
PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xylose SCHEMBL9723246 1.00 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL23066320 1.00 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL20298307 1.00 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL17376028 1.00 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL27662059 1.00 LMNA (0.46) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL9824366 0.98 LMNA (0.43) LMNAL3MBTL1TDP1AKR1B1KDM4E
Demannose SCHEMBL2341216 0.96 LMNA (0.48) LMNAL3MBTL1TDP1AKR1B1KDM4E
Demannose SCHEMBL9938071 0.96 LMNA (0.48) LMNAL3MBTL1TDP1AKR1B1KDM4E
Demannose SCHEMBL329074 0.93 LMNA (0.50) LMNAL3MBTL1TDP1AKR1B1KDM4E
Xylose SCHEMBL5322348 0.93 LMNA (0.43) LMNAL3MBTL1TDP1AKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-219744397-U Recovery system is escaped to separating centrifuge production xylose ethanol 高密同利制糖有限公司 2023-09-26 CN claimed
CN-117210484-A Method for promoting fermentation of saccharomyces cerevisiae xylose, constructed recombinant yeast strain and application thereof 上海交通大学 2023-12-12 CN disclosed
CN-219744397-U Recovery system is escaped to separating centrifuge production xylose ethanol 高密同利制糖有限公司 2023-09-26 CN disclosed
CN-219744397-U Recovery system is escaped to separating centrifuge production xylose ethanol 高密同利制糖有限公司 2023-09-26 CN disclosed
CN-116223733-B Quantitative characterization method for antagonism degree between xylose metabolism and robustness of Saccharomyces cerevisiae by C5/C6 co-utilization 齐鲁工业大学(山东省科学院) 2023-09-15 CN disclosed
CN-114317297-B High-yield ethanol fermentation strain and mutation breeding method thereof 广西科学院 2022-11-08 CN disclosed
CN-114317297-A High-yield ethanol fermentation strain and mutation breeding method thereof 广西科学院 2022-04-12 CN disclosed
EP-3559234-A1 RECOMBINANT YEAST STRAINS FOR PENTOSE FERMENTATION Novozymes A/S (DK) 2019-10-30 EP disclosed
CN-110055160-A Continuous cascaded immobilized reactant method and apparatus for cellulose alcoholic fermentation 北京师范大学 2019-07-26 CN disclosed
WO-2018114973-A1 RECOMBINANT YEAST STRAINS FOR PENTOSE FERMENTATION NOVOZYMES A/S (DK) 2018-06-28 WO disclosed
EP-2764085-A1 EUKARYOTIC CELL AND METHOD FOR PRODUCING GLYCOLIC ACID Teknologian tutkimuskeskus VTT (FI) 2014-08-13 EP disclosed
WO-2013176627-A1 XYLOSE FERMENTING YEAST CONSTRUCTED USING A MODIFIED GENOME SHUFFLING METHOD NGEE ANN POLYTECHNIC (SG) 2013-11-28 WO disclosed
CN-102046776-B Recombinant strain of the thermotolerant yeast hansenula polymorpha overexpressing xylose reductase, xylitol dehydrogenase and xylulokinase to promote xylose ethanol fermentation ARCHER DANIELS MIDLAND CO 2013-07-31 CN disclosed
WO-2013106113-A2 INTEGRATED PROCESSES FOR CONVERSION OF LIGNOCELLULOSIC BIOMASS TO BIOPRODUCTS AND SYSTEMS AND APPARATUS RELATED THERETO BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-07-18 WO disclosed
WO-2013050659-A1 EUKARYOTIC CELL AND METHOD FOR PRODUCING GLYCOLIC ACID TEKNOLOGIAN TUTKIMUSKESKUS VTT (FI) 2013-04-11 WO disclosed
WO-2012019308-A1 PROCESS FOR CO-FERMENTING GLUCOSE AND XYLOSE IOGEN ENERGY CORPORATION (CA) 2012-02-16 WO disclosed
WO-2009061746-A2 PROCESS FOR INTEGRATING CELLULOSE AND STARCH FEEDSTOCKS IN ETHANOL PRODUCTION ENERGY ENZYMES, INC. (US) 2009-05-14 WO disclosed
US-4612286-A Acid hydrolysis of biomass for alcohol production KAMYR, INC. (US) 1986-09-16 US disclosed
EP-0077394-A1 CONVERSION OF D-XYLOSE TO ETHANOL BY THE YEAST PACHYSOLEN TANNOPHILUS KURTZMAN, Cletus P. (US) 1983-04-27 EP disclosed
WO-1982003874-A1 CONVERSION OF D-XYLOSE TO ETHANOL BY THE YEAST PACHYSOLEN TANNOPHILUS KURTZMAN CLETUS P 1982-11-11 WO disclosed