Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324355 | 0.88 | MAPT (0.63) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL30198563 | 0.88 | MAPT (0.63) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL28038246 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL22094803 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL3538126 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL5374258 | 0.84 | MAPT (0.48) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL27646270 | 0.83 | MAPT (0.53) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6125268 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL10359737 | 0.83 | MAPT (0.65) | ALDH1A1MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL5201850 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MAPTCYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| EP-4153576-A1 | NOTCH INHIBITORS AND USES THEREOF | StemSynergy Therapeutics, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| CN-115836056-A | NOTCH inhibitors and uses thereof | STEMSYNERGY疗法有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| WO-2021237112-A1 | NOTCH INHIBITORS AND USES THEREOF | STEMSYNERGY THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2007097697-A1 | THERAPEUTIC QUINOLINE COMPOUNDS THAT ARE 5HT1B MODULATORS | ASTRAZENECA AB (SE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | ALDH1A1 2288/4885MAPT 3735/4885CYP1A2 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.