Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320260 | 0.91 | ALOX5 (0.48) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7831499 | 0.78 | HDAC1 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL12046948 | 0.72 | LMNA (0.68) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL6138793 | 0.71 | HDAC1 (0.56) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL6138801 | 0.71 | HDAC1 (0.56) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL8234055 | 0.71 | HDAC1 (0.79) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7829947 | 0.71 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7829459 | 0.71 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL23833005 | 0.71 | ALOX5 (0.52) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12046962 | 0.71 | LMNA (0.74) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113644-A2 | NEW HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-10-11 | — | — | WO | disclosed |