Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28620841 | 0.98 | PARP10 (0.62) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL29484786 | 0.96 | PARP10 (0.59) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL5323530 | 0.92 | PARP10 (0.60) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL16174814 | 0.85 | SMN1; SMN2 (0.55) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL8209000 | 0.85 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL70401 | 0.85 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9240757 | 0.85 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL6938784 | 0.84 | AKR1C3 (0.70) | PARP10SMN1; SMN2ERCC5FEN1AKR1C3 | |
| SCHEMBL29035397 | 0.84 | SMN1; SMN2 (0.58) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL8717537 | 0.84 | LMNA (0.67) | PARP10SRD5A2SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119191950-A | Asymmetric diaryl ketone compound and synthetic method thereof | 海南大学 | 2024-12-27 | — | — | CN | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |