Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PCNA | P12004 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324409 | 1.00 | SIRT5 (0.59) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL5324396 | 0.82 | SIRT5 (0.54) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL5324398 | 0.82 | SIRT5 (0.54) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL1572564 | 0.80 | KDM4E (0.56) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL31189933 | 0.80 | KDM4E (0.56) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL1572565 | 0.80 | KDM4E (0.56) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL10608422 | 0.79 | SLC7A5 (0.50) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL296690 | 0.79 | SLC7A5 (0.50) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL296983 | 0.79 | USP2 (0.53) | SIRT5SLC7A5THRBUSP2MEN1 | |
| SCHEMBL5320524 | 0.79 | SLC7A5 (0.50) | SIRT5SLC7A5THRBUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | SIRT5 4337/4885SLC7A5 3712/4885THRB 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.