Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962562 | 0.88 | SAT1 (0.45) | SAT1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL23219671 | 0.85 | GNAI3 (0.54) | SAT1GNAI3GNAO1GNAI1NAMPT | |
| SCHEMBL8551637 | 0.83 | — | — | |
| SCHEMBL6929311 | 0.83 | DRD4 (0.38) | DRD4PDCD1CD274NAMPTMAP4K4 | |
| SCHEMBL1249532 | 0.80 | DRD4 (0.36) | SAT1GNAI3GNAO1GNAI1DRD4 | |
| SCHEMBL8834672 | 0.77 | CASP2 (0.38) | SAT1GNAI3GNAO1GNAI1DRD4 | |
| SCHEMBL22481630 | 0.76 | EGLN2 (0.34) | DRD4NAMPTMAP4K4 | |
| SCHEMBL95570 | 0.75 | — | — | |
| SCHEMBL11420212 | 0.75 | SAT1 (0.60) | SAT1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL18236910 | 0.74 | GPR88 (0.36) | DRD4PDCD1CD274GPR88NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |
| EP-0649845-B1 | Furanyl insecticide | MITSUI CHEMICALS INC (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5532365-A | NITROGUANIDINE COMPOUNDS AS INSECTICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5434181-A | FOR USE IN AGRICULTURAL CHEMICALS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0649845-A1 | Furanyl insecticide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-04-26 | — | — | EP | disclosed |