Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325066 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL5329981 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL5326900 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL7912467 | 0.75 | KDM4E (0.73) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL11550658 | 0.73 | ADORA3 (0.68) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL5085543 | 0.71 | ERAP1 (0.63) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL7912397 | 0.71 | ADORA3 (0.59) | ALDH1A1KDM4EHSD17B10HPGDADORA3 | |
| SCHEMBL5327558 | 0.71 | TP53 (0.58) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| Chrysin Diacetate SCHEMBL15263635 | 0.68 | KDM4E (0.78) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL28421208 | 0.68 | ADORA3 (0.74) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |