Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471061 | 0.87 | ALDH1A1 (0.65) | ALDH1A1DNMT3ALMNAPSMB5KCNMA1 | |
| SCHEMBL5327174 | 0.87 | ALDH1A1 (0.51) | ALDH1A1DNMT3APSMB5ACACBFPR2 | |
| SCHEMBL14398212 | 0.84 | ALDH1A1 (0.48) | ALDH1A1DNMT3AACACB | |
| SCHEMBL5321332 | 0.83 | ALDH1A1 (0.59) | ALDH1A1DNMT3ALMNAPSMB5PPARG | |
| SCHEMBL5324896 | 0.83 | NR1H4 (0.55) | ALDH1A1DNMT3APSMB5PPARGACACB | |
| SCHEMBL5325179 | 0.83 | NR1H4 (0.55) | ALDH1A1DNMT3APSMB5PPARGACACB | |
| SCHEMBL5326665 | 0.83 | NR1H4 (0.55) | ALDH1A1DNMT3APSMB5PPARGACACB | |
| SCHEMBL5324806 | 0.81 | ALDH1A1 (0.48) | ALDH1A1DNMT3APPARGRAB9ANCOA3 | |
| SCHEMBL5325161 | 0.81 | ACACB (0.48) | ALDH1A1DNMT3APSMB5L3MBTL1ACACB | |
| SCHEMBL14397665 | 0.81 | KMT2A (0.60) | ALDH1A1LMNAL3MBTL1RAB9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | claimed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |