Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetaminophen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | CA12 | O43570 | 1/20 | 0.83 |
| ▸ | BRD4 | O60885 | 1/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.83 |
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | MB | P02144 | 1/20 | 0.83 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.83 |
| ▸ | CA3 | P07451 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | RARG | P13631 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.83 |
| ▸ | CA4 | P22748 | 1/20 | 0.83 |
| ▸ | CA7 | P43166 | 1/20 | 0.83 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaminophen SCHEMBL3480 | 0.91 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL252939 | 0.91 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8937727 | 0.91 | KMT2A (1.00) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8197085 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL20541508 | 0.89 | ALDH1A1 (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL10325382 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL31738441 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL5081499 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8959271 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 | |
| Acetaminophen SCHEMBL8207526 | 0.89 | KMT2A (0.95) | KMT2AALDH1A1MAPTMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136307-A | Methods, assays and systems for detecting target analytes | 索伦托治疗有限公司 | 2023-11-28 | — | — | CN | claimed |
| EP-4278183-A1 | METHODS, ASSAYS AND SYSTEMS FOR DETECTION OF A TARGET ANALYTE | Sorrento Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | claimed |
| WO-2022155380-A1 | METHODS, ASSAYS AND SYSTEMS FOR DETECTION OF A TARGET ANALYTE | VIREX HEALTH, INC. (US) | 2022-07-21 | — | — | WO | claimed |
| US-20210292353-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-09-23 | — | — | US | claimed |
| EP-3829565-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | Karlsruher Institut für Technologie (DE) | 2021-06-09 | — | — | EP | claimed |
| WO-2020025488-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | Karlsruher Institut für Technologie (DE) | 2020-02-06 | — | — | WO | claimed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | claimed |
| CN-101395473-A | Water-soluble conjugates for electrochemical detection | INVILLNIS MEDICINE SWISS CO LT (CH) | 2009-03-25 | — | — | CN | claimed |
| WO-2007123507-A1 | WATER-SOLUBLE CONJUGATES FOR ELECTROCHEMICAL DETECTION | INVERNESS MEDICAL SWITZERLAND GMBH (CH) | 2007-11-01 | — | — | WO | claimed |
| US-20060205090-A1 | Water-soluble conjugates for electrochemical detection | OAKVILLE HONG KONG COMPANY LIMITED (HK) | 2006-09-14 | — | — | US | claimed |
| CN-117136307-A | Methods, assays and systems for detecting target analytes | 索伦托治疗有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4278183-A1 | METHODS, ASSAYS AND SYSTEMS FOR DETECTION OF A TARGET ANALYTE | Sorrento Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022155380-A1 | METHODS, ASSAYS AND SYSTEMS FOR DETECTION OF A TARGET ANALYTE | VIREX HEALTH, INC. (US) | 2022-07-21 | — | — | WO | disclosed |
| CN-112899640-B | Preparation and application of nanocrystalline graphite/boron-doped diamond composite material | 吉林大学 | 2022-02-18 | — | — | CN | disclosed |
| US-20210292353-A1 | INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-09-23 | — | — | US | disclosed |
| EP-0759171-A1 | PARACETAMOL PHOSPHATE FOR IMMUNOASSAYS | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1997-02-26 | — | — | EP | disclosed |
| EP-0759171-A1 | PARACETAMOL PHOSPHATE FOR IMMUNOASSAYS | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995031724-A1 | PARACETAMOL PHOSPHATE FOR IMMUNOASSAYS | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1995-11-23 | — | — | WO | disclosed |
| WO-1995031724-A1 | PARACETAMOL PHOSPHATE FOR IMMUNOASSAYS | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1995-11-23 | — | — | WO | disclosed |
| US-4322410-A | P-Acetaminophenyl phosphate salts as analgesics and antipyretics | Dugniolle, Jacques (FR) | 1982-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112948-A1 | Inorganic-organic hybrid compound | SLCO4C1, SLCO2A1, SLCO1A2 | KMT2A 3120/4885ALDH1A1 980/4885MAPT 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.