Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | DRD1 | P21728 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 3/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689417 | 0.88 | DRD1 (0.65) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL31029778 | 0.85 | KDM4E (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL27987614 | 0.84 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL25844515 | 0.84 | DRD2 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL29886755 | 0.84 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL14367906 | 0.84 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL14259791 | 0.84 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL29402012 | 0.84 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL30828734 | 0.83 | DRD1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Actinodaphnine SCHEMBL674832 | 0.82 | KDM4E (1.00) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134485-A1 | APORPHINE AND OXOAPORPHINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | LOTUS PHARMACEUTICAL CO., LTD. (CN) | 2007-11-29 | — | — | WO | disclosed |