Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330099 | 0.82 | L3MBTL1 (1.00) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8031188 | 0.76 | RAB9A (0.65) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| Ammonia Solution, Strong SCHEMBL10619768 | 0.74 | RAB9A (0.63) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| Ammonia Solution, Strong SCHEMBL10619764 | 0.74 | RAB9A (0.63) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28095616 | 0.73 | RAB9A (0.62) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| Benzothiazyl Disulfide SCHEMBL28178074 | 0.73 | ALDH1A1 (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28433258 | 0.73 | ALDH1A1 (0.68) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14345990 | 0.72 | L3MBTL1 (0.80) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28238554 | 0.72 | L3MBTL1 (0.80) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12210186 | 0.71 | HPGD (0.73) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |