Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326201 | 0.85 | HTR2C (0.45) | NMT2NMT1 | |
| SCHEMBL5345157 | 0.83 | DRD2 (0.47) | NMT2NMT1APPIDO1TDO2 | |
| SCHEMBL27893573 | 0.82 | NMT2 (0.50) | NMT2NMT1APPIDO1TDO2 | |
| SCHEMBL27621992 | 0.81 | NMT2 (0.50) | NMT2NMT1APP | |
| Hydrochloric Acid SCHEMBL27873356 | 0.81 | NMT2 (0.49) | NMT2NMT1APPIDO1TDO2 | |
| Hydrochloric Acid SCHEMBL2034993 | 0.81 | NMT2 (0.42) | NMT2NMT1APPIDO1TDO2 | |
| SCHEMBL13645914 | 0.78 | CHRNB2 (0.44) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3861904 | 0.77 | CHRNB2 (0.43) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5324244 | 0.76 | HTR2C (0.55) | — | |
| SCHEMBL27669377 | 0.74 | KMT2A (0.46) | NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |