Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325602 | 0.85 | NMT2 (0.43) | NMT2NMT1 | |
| SCHEMBL6223816 | 0.83 | HTR1F (0.49) | HTR2CALDH1A1NMT2NMT1 | |
| SCHEMBL4617058 | 0.83 | DRD2 (0.50) | HTR2CKMT2AALDH1A1 | |
| SCHEMBL4615264 | 0.82 | NPC1 (0.50) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13646074 | 0.78 | HTR2C (0.47) | HTR2CPLATMEN1KMT2ACHRNB2 | |
| SCHEMBL5324244 | 0.77 | HTR2C (0.55) | HTR2CALDH1A1 | |
| SCHEMBL31406453 | 0.76 | CA12 (0.55) | MEN1KMT2A | |
| SCHEMBL16292956 | 0.75 | HTR2C (0.51) | HTR2C | |
| SCHEMBL1440072 | 0.74 | CA12 (0.46) | — | |
| SCHEMBL30242035 | 0.74 | CA12 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114902-A2 | ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS | H.LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |