Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.55 |
| ▸ | WNT3A | P56704 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470481 | 0.91 | PDE4D (0.54) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL10729104 | 0.88 | THRA (0.54) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL6588871 | 0.88 | CA12 (0.57) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL11619672 | 0.86 | CTNNB1 (0.54) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL11476787 | 0.84 | GSK3B (0.54) | CTNNB1WNT3ATSHRCA12CA1 | |
| SCHEMBL30313764 | 0.83 | CTNNB1 (0.71) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL6600362 | 0.83 | CTNNB1 (0.71) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL5729109 | 0.83 | ALDH1A1 (0.65) | CTNNB1WNT3APDE4DPDE4APDE4B | |
| SCHEMBL8962350 | 0.82 | HPGD (0.54) | TSHRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL901309 | 0.81 | CA12 (0.71) | TSHRCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| US-4127666-A | ANTIEMETIC | UNIVERSITE D'ORLEANS (FR) | 1978-11-28 | — | — | US | disclosed |