Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325385 | 0.83 | CTSS (0.48) | CTSSKAT6AEPHX2PPARG | |
| SCHEMBL14399347 | 0.80 | CTSS (0.48) | CTSSEPHX2PPARG | |
| SCHEMBL5325964 | 0.80 | POLB (0.61) | OPRM1OPRD1OPRK1POLBNPC1 | |
| SCHEMBL13753372 | 0.79 | CTSS (0.65) | CTSSKAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12654656 | 0.78 | CNR2 (0.50) | CTSSEPHX2CTSKNPC1RAB9A | |
| SCHEMBL13753422 | 0.78 | CTSS (0.64) | CTSSKAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5324074 | 0.76 | CDK2 (0.54) | CDK2NPC1RAB9APPARG | |
| SCHEMBL5331315 | 0.76 | CDK2 (0.52) | CDK2POLBNPC1RAB9A | |
| SCHEMBL24862943 | 0.76 | NPC1 (0.50) | OPRM1OPRD1OPRK1POLBNPC1 | |
| SCHEMBL24862953 | 0.75 | ALDH1A1 (0.51) | OPRM1OPRD1OPRK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |