Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187086 | 0.83 | L3MBTL1 (0.44) | L3MBTL1NPSR1SMN1; SMN2PKMCYP3A4 | |
| SCHEMBL1226938 | 0.83 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2PKMAKR1C3AKR1C2 | |
| SCHEMBL20267146 | 0.81 | ALDH1A1 (0.50) | L3MBTL1NPSR1CYP3A4BLMALDH1A1 | |
| SCHEMBL20267144 | 0.81 | ALDH1A1 (0.50) | L3MBTL1NPSR1CYP3A4BLMALDH1A1 | |
| SCHEMBL2467334 | 0.77 | CDC25A (0.54) | L3MBTL1AKR1C3AKR1C2ALDH1A1CDC25A | |
| SCHEMBL28030373 | 0.75 | CYP3A4 (0.56) | L3MBTL1NPSR1SMN1; SMN2PKMCYP3A4 | |
| SCHEMBL28259386 | 0.73 | HTR2A (0.46) | L3MBTL1CYP3A4BLMALDH1A1TSHR | |
| SCHEMBL28521498 | 0.72 | TDP1 (0.54) | L3MBTL1NPSR1SMN1; SMN2PKMCYP3A4 | |
| SCHEMBL5742862 | 0.72 | OXER1 (0.41) | L3MBTL1AKR1C3AKR1C2ALDH1A1CDC25A | |
| SCHEMBL5814849 | 0.71 | ALDH1A1 (0.44) | L3MBTL1AKR1C3AKR1C2ALDH1A1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098356-A1 | CONGENERS OF MILNACIPRAN AS MONOAMINE RE-UPTAKE | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |