Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703744 | 0.77 | TSHR (0.57) | KEAP1IL1RNERAP1ALDH1A1MEN1 | |
| SCHEMBL4338778 | 0.75 | POLB (0.39) | ALDH1A1MEN1KMT2APKMRXFP1 | |
| SCHEMBL5394291 | 0.74 | CYP19A1 (0.52) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL32679819 | 0.74 | CA1 (0.45) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL28112391 | 0.74 | KEAP1 (0.45) | KEAP1ALDH1A1CA1CA2CA12 | |
| SCHEMBL9043155 | 0.73 | SLC40A1 (0.53) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL27827381 | 0.72 | PSIP1 (0.44) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL5402624 | 0.72 | PTGES2 (0.51) | CA2MMP1MMP8MMP13 | |
| SCHEMBL25031372 | 0.70 | KEAP1 (1.00) | KEAP1IL1RNERAP1ALDH1A1MEN1 | |
| SCHEMBL810795 | 0.70 | KMT2A (0.91) | KEAP1IL1RNERAP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470993-A | The azepine quinazoline inhibitor of Atypical protein kinase C | 癌症研究科技有限公司 | 2017-03-01 | — | — | CN | disclosed |
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |