Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320636 | 0.89 | CSNK2A1 (0.48) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL5325828 | 0.88 | CSNK2A1 (0.47) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL5323448 | 0.88 | CSNK2A1 (0.47) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL5321374 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL976567 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1HPGDMAPK1KMT2A | |
| SCHEMBL5326148 | 0.73 | CDK2 (0.43) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL5594559 | 0.71 | CSNK2A1 (0.43) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL14014371 | 0.70 | KDM4E (0.59) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL14463752 | 0.67 | CDK2 (0.54) | KDM4EALDH1A1HPGDGLAMAPK1 | |
| SCHEMBL12953150 | 0.65 | CSNK2A1 (0.71) | KDM4EALDH1A1HPGDGLAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118844-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING HARMFUL FUNGI AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2007-10-25 | — | — | WO | disclosed |