Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ILK | Q13418 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770980 | 0.83 | KDM4E (0.57) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL900528 | 0.81 | KDM4E (0.44) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2137490 | 0.75 | KDM4E (0.69) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL713163 | 0.73 | RAB9A (0.50) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL827403 | 0.73 | RAB9A (0.67) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12474389 | 0.73 | PTGS1 (0.46) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12474338 | 0.73 | NPC1 (0.40) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20855087 | 0.72 | ALDH1A1 (0.54) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7110707 | 0.72 | KDM4E (0.56) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10414016 | 0.71 | KDM4E (0.64) | RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| US-4665162-A | DYES FOR LEATHER AND PAPER | SANDOZ LTD. (CH) | 1987-05-12 | — | — | US | claimed |
| CN-108658982-A | A kind of synthetic method of novel 3- (benzothiazolyl) imidazo [1,2-a] pyridines bis-heterocyclic compounds | 河南工业大学 | 2018-10-16 | — | — | CN | disclosed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-4665162-A | DYES FOR LEATHER AND PAPER | SANDOZ LTD. (CH) | 1987-05-12 | — | — | US | disclosed |
| US-4587292-A | AZO DYES | SANDOZ LTD. (CH) | 1986-05-06 | — | — | US | disclosed |
| US-4550158-A | DYE FOR PAPER AND LEATHER | SANDOZ LTD. (CH) | 1985-10-29 | — | — | US | disclosed |