SCHEMBL2137490

SCHEMBL2137490

Cc1ccccc1-c1nc2ccccc2s1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.69
NPC1 O15118 7/20 0.69
RAB9A P51151 7/20 0.69
ALDH1A1 P00352 6/20 0.69
MAPT P10636 6/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
GAA P10253 3/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
TDP1 Q9NUW8 1/20 0.69
ILK Q13418 3/20 0.59
POLB P06746 1/20 0.56
GLA P06280 2/20 0.55
HCRTR1 O43613 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
TP53 P04637 3/20 0.54
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9464517 0.88 KDM4E (0.63) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL23677964 0.88 KDM4E (0.63) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL21742670 0.86 RAB9A (0.61) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL231307 0.86 KDM4E (0.75) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL10414016 0.85 KDM4E (0.64) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL7192851 0.85 RAB9A (0.68) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL12854008 0.84 KDM4E (0.72) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL2139104 0.83 MAPT (0.57) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL23176467 0.83 MAPT (0.55) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL21742669 0.82 RAB9A (0.60) KDM4ENPC1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310089-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2024-01-24 EP disclosed
US-20230141905-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
CN-108250157-B Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium 江西师范大学 2021-12-21 CN disclosed
CN-110156716-B Synthetic method of benzothiazole ester derivative 安徽师范大学 2021-08-27 CN disclosed
US-20210257564-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION CONTAINING THE COMPOUND AND SOLVENT, ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE COMPOUND, DISPLAY DEVICE, AND ILLUMINATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2021-08-19 US disclosed
US-11038126-B2 Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device, and illumination device MITSUBISHI CHEMICAL CORPORATION (JP) 2021-06-15 US disclosed
EP-3164898-B1 ORGANIC LIGHT-EMITTING DIODE (OLED) INCLUDING AN ELECTRON TRANSPORT LAYER STACK COMPRISING DIFFERENT LITHIUM COMPOUNDS NOVALED GMBH (DE) 2021-05-12 EP disclosed
US-20200274078-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION CONTAINING THE COMPOUND AND SOLVENT, ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE COMPOUND, DISPLAY DEVICE, AND ILLUMINATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2020-08-27 US disclosed
EP-3637489-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-04-15 EP disclosed
CN-110156716-A A kind of synthetic method of benzothiazole ester derivative 安徽师范大学 2019-08-23 CN disclosed
US-20090114355-A1 ORGANIC FLUORESCENT COMPOSITIONS HONEYWELL INTERNATIONAL INC. (US) 2009-05-07 US disclosed
EP-1300396-B1 1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF EISAI R&D MAN CO LTD (JP) 2009-01-14 EP disclosed
EP-1465626-B1 PHARMACEUTICAL COMPOSITIONS (KIT) COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY (OR AN ANTIINFLAMMATORY) AGENT AND THEIR USES EISAI R&D MAN CO LTD (JP) 2008-09-03 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20050096471-A1 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed
EP-1473286-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-03 EP disclosed
WO-2003047577-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES EISAI CO LTD (JP) 2003-06-12 WO disclosed
US-3962056-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 US disclosed
US-3962055-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210257564-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION CONTAINING THE COMPOUND AND SOLVENT, ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE COMPOUND, DISPLAY DEVICE, AND ILLUMINATION DEVICE RB1, ARL1, CDKL1 KDM4E 2827/4885NPC1 4417/4885RAB9A 870/4885
US-20090114355-A1 ORGANIC FLUORESCENT COMPOSITIONS PFAS, FUS, ACR KDM4E 3212/4885NPC1 425/4885RAB9A 2507/4885
US-11038126-B2 Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device, and illumination device ACVRL1, CCNL2, CXCR1 KDM4E 4283/4885NPC1 4637/4885RAB9A 3252/4885
US-20050096471-A1 Process for producing biaryl compound PPOX, CAT, TYR KDM4E 3428/4885NPC1 4102/4885RAB9A 2254/4885
US-20200274078-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION CONTAINING THE COMPOUND AND SOLVENT, ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE COMPOUND, DISPLAY DEVICE, AND ILLUMINATION DEVICE ACVRL1, CCNL2, CXCR1 KDM4E 4283/4885NPC1 4637/4885RAB9A 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.