Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | GHSR | Q92847 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691241 | 0.82 | ATM (0.76) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL2883579 | 0.82 | HRH3 (0.56) | LMNAHTR2AKDM4EALDH1A1HTT | |
| SCHEMBL7311276 | 0.81 | ATM (0.84) | ATMMEN1KMT2AKCNH2HDAC1 | |
| Belarizine SCHEMBL2108057 | 0.80 | ATM (0.73) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL16226642 | 0.80 | ATM (0.68) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL12464946 | 0.80 | KCNH2 (0.80) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL16226272 | 0.80 | LMNA (0.70) | ATMMEN1KMT2AKCNH2HDAC1 | |
| Hydrochloric Acid SCHEMBL16226937 | 0.80 | ATM (0.82) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL8690003 | 0.80 | ATM (0.67) | ATMMEN1KMT2AKCNH2HDAC1 | |
| SCHEMBL8744969 | 0.80 | ATM (0.67) | ATMMEN1KMT2AKCNH2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276732-B1 | AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION\ | DOMPE PHA R MA SPA RES & MFG (IT) | 2007-09-26 | — | — | EP | disclosed |