Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.67 |
| ▸ | HRH1 | P35367 | 5/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 2/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.67 |
| ▸ | GHSR | Q92847 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691241 | 0.94 | ATM (0.76) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL12464946 | 0.89 | KCNH2 (0.80) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL8744968 | 0.87 | HRH1 (0.64) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL588111 | 0.87 | KCNH2 (0.78) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL588110 | 0.87 | KCNH2 (0.78) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL3611802 | 0.87 | KCNH2 (0.78) | ATMHRH1KCNH2ADORA3CNR1 | |
| SCHEMBL9720751 | 0.86 | KCNH2 (0.71) | ATMHRH1KCNH2ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL587709 | 0.85 | LMNA (0.79) | ATMHRH1KCNH2ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588103 | 0.85 | LMNA (0.79) | ATMHRH1KCNH2ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588128 | 0.85 | LMNA (0.79) | ATMHRH1KCNH2ADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |