Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.45 |
| ▸ | THRA | P10827 | 8/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328904 | 0.90 | THRB (0.50) | THRBTHRARORC | |
| SCHEMBL5326859 | 0.89 | THRB (0.46) | THRBTHRARORC | |
| SCHEMBL5327813 | 0.88 | THRB (0.56) | THRBTHRA | |
| SCHEMBL5327791 | 0.80 | THRB (0.67) | THRBTHRA | |
| SCHEMBL5330306 | 0.80 | THRB (0.43) | THRBTHRARORCCRHR1 | |
| SCHEMBL5323874 | 0.78 | RORC (0.55) | THRBTHRARORC | |
| SCHEMBL5326809 | 0.77 | THRB (0.46) | THRBTHRA | |
| SCHEMBL5324510 | 0.73 | THRB (0.38) | THRBTHRARORC | |
| SCHEMBL1992687 | 0.70 | MEN1 (0.41) | TSHRMAPK1 | |
| SCHEMBL5326865 | 0.69 | RORC (0.46) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |