Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 7/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328906 | 0.90 | THRB (0.48) | THRBRORCGAATHRA | |
| SCHEMBL5326865 | 0.89 | RORC (0.46) | THRBMEN1POLBRECQLKMT2A | |
| SCHEMBL5327815 | 0.88 | THRB (0.53) | THRBTHRA | |
| SCHEMBL5327796 | 0.80 | THRB (0.64) | THRBTHRA | |
| SCHEMBL5327062 | 0.80 | THRB (0.45) | THRBRORCTHRACRHR1 | |
| SCHEMBL5323878 | 0.78 | RORC (0.55) | THRBRORCTHRA | |
| SCHEMBL5326814 | 0.77 | THRB (0.46) | THRBMEN1POLBRECQLKMT2A | |
| SCHEMBL5326880 | 0.73 | RORC (0.38) | THRBMEN1POLBRECQLKMT2A | |
| SCHEMBL7555866 | 0.69 | THRB (0.47) | THRBMEN1KMT2ARORCTHRA | |
| SCHEMBL5326859 | 0.69 | THRB (0.46) | THRBRORCTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |