Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.68 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.68 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.68 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.68 |
| ▸ | LDHA | P00338 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.68 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.68 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926920 | 1.00 | P2RY1 (0.68) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL6569310 | 0.88 | ADORA1 (0.73) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL8708990 | 0.87 | ADORA1 (0.71) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL939593 | 0.87 | ADORA1 (0.71) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL1723484 | 0.87 | P2RY1 (0.70) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL8582406 | 0.86 | P2RY1 (0.72) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL4870935 | 0.86 | P2RY1 (0.72) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL3699269 | 0.86 | P2RY1 (0.68) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL4650247 | 0.86 | IARS1 (0.69) | P2RY1ADORA1P2RY2SMN1; SMN2SRC | |
| SCHEMBL1000175 | 0.86 | P2RY1 (0.68) | P2RY1ADORA1P2RY2SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135380-A2 | ANTIPARASITIC COMPOUNDS AND COMPOSITIONS | MEDICAL RESEARCH COUNCIL (GB) | 2007-11-29 | — | — | WO | disclosed |
| US-RE37045-E1 | N-6 substituted-5′-(N-substituted carboxamide)adenosines as cardiac vasodilator and antihypertensive agents | DISCOVERY THERAPEUTICS, INC. | 2001-02-06 | — | — | US | disclosed |
| WO-1995002604-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5310731-A | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents | WHITBY RESEARCH, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0191025-B1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | Whitby Research Incorporated (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0191025-A1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS. | NELSON RES & DEV (US) | 1986-08-20 | — | — | EP | disclosed |
| WO-1986000310-A1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1986-01-16 | — | — | WO | disclosed |