Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385734 | 0.94 | ALDH1A1 (0.44) | ALDH1A1ENPEPGSTK1LMNASLC22A6 | |
| SCHEMBL5324634 | 0.90 | GABRP (0.43) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9537924 | 0.79 | HMGCR (0.42) | CTSAACHEHMGCR | |
| SCHEMBL8383711 | 0.78 | HMGCR (0.39) | CTSAACHEHMGCR | |
| SCHEMBL8383658 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL8383303 | 0.75 | HMGCR (0.40) | CTSAACHEHMGCRPOLB | |
| SCHEMBL8381798 | 0.74 | FDPS (0.39) | CTSAACHEHMGCR | |
| SCHEMBL1846885 | 0.74 | FFAR4 (0.44) | ALDH1A1LMNASLC22A6TSHR | |
| SCHEMBL13658757 | 0.74 | LMNA (0.53) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL18985287 | 0.74 | GABRP (0.37) | FOLH1ALDH1A1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138381-A2 | PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-12-06 | — | — | WO | disclosed |
| US-5962438-A | OSTEOPOROSIS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0827951-A1 | NOVEL BONE-SEEKING ESTROGEN DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |