Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332248 | 0.92 | HTR6 (0.44) | HTR6MAPTTP53GAAHPGD | |
| SCHEMBL5333172 | 0.89 | HTR6 (0.54) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5331698 | 0.89 | HTR6 (0.54) | HTR6MAPTGAAHPGDALDH1A1 | |
| SCHEMBL5330895 | 0.88 | HTR6 (0.41) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5327666 | 0.82 | HTR6 (0.48) | HTR6MAPTHDAC1HDAC2HDAC6 | |
| SCHEMBL5336640 | 0.81 | HTR6 (0.50) | HTR6HDAC1HDAC2HDAC6HTR1A | |
| SCHEMBL5333545 | 0.81 | HTR6 (0.41) | HTR6MAPTALDH1A1LMNA | |
| SCHEMBL5328011 | 0.81 | HTR6 (0.52) | HTR6MAPTTP53GLAGAA | |
| SCHEMBL5324143 | 0.81 | HTR6 (0.42) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL5331545 | 0.81 | HTR6 (0.51) | HTR6HDAC1HDAC2HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |