SCHEMBL2592352

SCHEMBL2592352

Cc1ccc(OC(=O)CN)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
GAA P10253 3/20 0.56
KMT2A Q03164 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5842867 0.83 LMNA (0.56) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL645265 0.83 KMT2A (0.69) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL241601 0.83 LMNA (0.61) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL10907507 0.82 LMNA (0.61) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL11151702 0.81 KMT2A (0.45) LMNAGAAKMT2ATDP1ALDH1A1
SCHEMBL561023 0.81 KMT2A (0.45) LMNAGAAKMT2ATDP1ALDH1A1
SCHEMBL11773507 0.81 KMT2A (0.45) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL28183303 0.81 LMNA (0.59) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL2239096 0.81 KMT2A (0.66) LMNAGAAKMT2AL3MBTL1TDP1
SCHEMBL10593101 0.80 KMT2A (0.57) LMNAGAAKMT2AL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4659751-A Simplified method for obtained strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1987-04-21 US claimed
JP-1144487-A None JP disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
CN-113004162-B Preparation method of asymmetric gem diaryl acetate compound 苏州大学 2023-05-05 CN disclosed
CN-115989341-A Method for manufacturing structure with conductive pattern 旭化成株式会社 2023-04-18 CN disclosed
WO-2022145400-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS 三光株式会社 2022-07-07 WO disclosed
WO-2022098371-A1 PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT YAN MATTHEW (US) 2022-05-12 WO disclosed
WO-2021142244-A1 SKIN TREATMENT METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS TOPIX PHARMACEUTICALS, INC. (US) 2021-07-15 WO disclosed
CN-113004162-A Preparation method of asymmetric geminal diaryl acetate compound 苏州大学 2021-06-22 CN disclosed
US-20150257986-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS ADA FOUNDATION 2015-09-17 US disclosed
EP-2563324-A1 COSMETIC COMPOSITION CONTAINING OLIGOPEPTIDES Cognis IP Management GmbH (DE) 2013-03-06 EP disclosed
WO-2011134568-A1 COSMETIC COMPOSITION CONTAINING OLIGOPEPTIDES COGNIS IP MANAGEMENT GMBH (DE) 2011-11-03 WO disclosed
CN-102093363-A Pyrrolo-triazine aniline compounds useful as kinase inhibitors BRISTOL MYERS SQUIBB CO 2011-06-15 CN disclosed
CN-1662509-A Pyrrolotriazine aniline compounds useful as kinase inhibitors BRISTOL MYERS SQUIBB CO (US) 2005-08-31 CN disclosed
CN-1135333-A Usage of SRCSH2 specific compound for treatment of bone absorption disease SMITHKLINE BEECHAM CORP (US) 1996-11-13 CN disclosed
JP-H01144487-A PRODUCT FOR MANUFACTURING SURFACE OF SUBSTRATE DEN MAT CORP 1989-06-06 JP disclosed
US-4588756-A Multi-step method for obtaining strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1986-05-13 US disclosed
US-4088657-A FROM AN ALIPHATIC NITRILE AND GLYCOLIC ACID IN SULFURIC ACID, CONDENSING WITH AN AROMATIC HYDROCARBON OR THIOPHENE NOBEL HOECHST CHIMIE (FR) 1978-05-09 US disclosed
US-RE29213-E TRIMELLITIC ANHYDRIDE, DIISOCYANATE, GLYCINE DERIVATIVE SCHENECTADY CHEMICALS, INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150257986-A1 ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS ESD, JMJD6, DNPH1 LMNA 1826/4885GAA 157/4885KMT2A 929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.