SCHEMBL12654656

SCHEMBL12654656

CC(Cc1ccc(Cl)cc1)NC(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.50
CTSS P25774 3/20 0.48
ACACB O00763 1/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.48
CTSK P43235 2/20 0.46
P2RX7 Q99572 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
HSD17B2 P37059 1/20 0.44
PPARG P37231 2/20 0.44
FPR2 P25090 1/20 0.44
PPARA Q07869 1/20 0.44
ITGB1 P05556 1/20 0.43
ITGA4 P13612 1/20 0.43
EPHX2 P34913 1/20 0.43
USP36 Q9P275 1/20 0.42
GRM5 P41594 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1949839 0.83 HDAC8 (0.48) CTSSLMNAGAACTSKEPHX2
SCHEMBL1816209 0.83 ACACB (0.53) ACACBP2RX7NPC1RAB9AFPR2
SCHEMBL12654827 0.82 ACACB (0.50) CNR2ACACBLMNANPC1RAB9A
SCHEMBL12621261 0.82 UTS2R (0.54) CTSSACACBCTSKP2RX7NPC1
SCHEMBL12654826 0.81 ACACB (0.51) ACACBLMNANPC1RAB9AFPR2
SCHEMBL24567557 0.80 MEN1 (0.65) CTSSLMNAGAACTSKRAB9A
SCHEMBL5328209 0.78 CTSS (0.56) CTSSCTSKNPC1RAB9APPARG
SCHEMBL1835535 0.78 LMNA (0.54) CTSSLMNAGAACTSK
SCHEMBL11921044 0.77 GAA (0.42) CTSSACACBLMNAGAANPC1
SCHEMBL16235119 0.77 TRPA1 (0.65) CTSSLMNAGAACTSKP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951973-B2 N-(1-methyl-2Phenylethyl)benzamide derivatives BAYER CROPSCIENCE AG (DE) 2011-05-31 US disclosed